Nancy Klein, MD
Specialties-Reproductive Endocrinology & Infertility
- Assisted reproductive technologies, IVF
- Age-related infertility and egg donation
- Anovulation, irregular menstruation and ovulation induction with injections and oral fertility drugs, such as Clomid
Licensure
- Washington, 1993
Board Certification
- Obstetrics and Gynecology, 1995
- Reproductive Endocrinology and Infertility, 1998
Education
- MD degree (Vanderbilt University Medical School, 1985)
- Residency in Obstetrics and Gynecology (University of Tennessee, 1990)
- Fellowship in Reproductive Endocrinology and Infertility (University of Texas, 1993)
Research Interests
- Reproductive aging
- Assisted Reproductive Technologies (ART)
- Aging of the Normal Human Ovary from Birth to Menopause
Affiliations
- American College of Obstetricians and Gynecologists
- American Society for Reproductive Medicine
- Society for Assisted Reproductive Technologies
- Pacific Coast Reproductive Society
- Society for Gynecologic Investigation
- Society of Reproductive Endocrinology and Infertility
Honors
- Past NIH grant recipient
- ASRM prize paper recipient 2003, 2006
- Seattle Magazine Top Doctors for Women 2003
- Seattle Magaine Top Doctors 2006, 2007
- Seattle Metropolitan Magazine Top Doctors 2007
Publications
Klein NA, Battaglia DE, Clifton DK, Bremner WJ, Soules MR. The gonadotropin secretion pattern in normal women of advanced reproductive age in relation to the monotropic FSH rise. J Soc Gynecol Invest 1996;3:27-32.
Fujimoto VY, Klein NA, Davis GS, Bremner WJ, Soules MR. Attenuated release of pituitary luteinizing hormone in older reproductive-age women in response to GnRH stimulation. Fertil Steril 1996;65:539-544.
Klein NA, Battaglia DE, Fujimoto VY, Clifton DK, Davis GS, Bremner WJ, Soules MR. Reproductive aging: accelerated ovarian follicular development associated with the monotropic FSH rise in normal older women. J Clin Endocrinol Metab 1996;81:1038-1045.
Klein NA, Battaglia DE, Miller PB, Soules MR. Circulating levels of growth hormone, IGF-I, and growth hormone binding protein in normal women of advanced reproductive age. Clin Endo 1996; 44:285-292.
Klein NA, Battaglia DE, Miller PB, Giudice LC, Soules MR. Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age. J Clin Endocrinol Metab 1996;81:1946-51.
Klein NA, Illingworth PJ, Groome NP, McNeilly AS, Battaglia DE, Soules MR. Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles. J Clin Endocrinol Metab 1996;81:2742-2745.
Battaglia DE, Goodwin P, Klein NA, Soules MR. Influence of maternal age on meiotic spindle assembly in the human oocyte. Human Reprod 1996;11:2217.
Battaglia DE, Klein NA, Soules MR. Changes in centrosomal domains during meiotic maturation in the human oocyte. Molecular Hum Reprod 1997;2:845-851.
Klein NA, Battaglia DE, Woodruff TK, Padmanabhan V, Giudice LC, Groome NP, Bremner WJ, Soules MR. Ovarian follicular concentrations of follistatin, inhibin, IGF-I, IGF-II, IGFBP-2, IGFBP-3, and VEGF in spontaneous menstrual cycles of normal women of advanced reproductive age. J Clin Endocrinol Metab, 2000;85:4520-4525.
Klein NA, Harper AJ, Houmard BS, Soules MS. Is the short follicular phase in older women secondary to advanced or accelerated dominant follicle development? J Clin Endocrinol Metab, in press.
