Michael Soules, MD
Managing Partner of Seattle Reproductive Medicine
Specialties: Reproductive Endocrinology & Infertility
- Assisted reproductive technologies, including IVF
- Uterine anomalies
- Polycystic ovarian syndrome
- Ovarian Aging
- Endometriosis
- Menstrual cycle abnormalities
- Complex infertility problems with multiple problems
- Luteal phase deticipucy
Licensure
- State of Washington, 1980
Board Certification
- Obstetrics and Gynecology, 1979 (recertified 1993)
- Reproductive Endocrinology and Infertility, 1981 (recertified 1993, 1999, 2002)
Education
- MD degree (University of California Los Angeles, 1972)
- Residency in Obstetrics and Gynecology (University of Colorado, 1976)
- Fellowship in Reproductive Endocrinology and Infertility (Duke University, 1978)
- Management Program (School of Business, University of Washington, 1990)
Research Interests
- Reproductive aging
- Luteal phase deficiency
- Inhibin/activin
Current Research
- Reproductive Aging in Normal Premenopausal Women
- New Protocol for IVF Ovulation Induction
- Acqueous Progesterone for use in ART
Affiliations
- American College of Obstetricians and Gynecologists
- American Society for Reproductive Medicine
- Pacific Coast Reproductive Society
- Society of Reproductive Endocrinology and Infertility
- Society for Gynecologic Investigation
- American Gynecological and Obstetrical Society
- European Society of Human Reproduction and Embryology
- International Federation of Gynecology and Obstetrics
- King County Medical Society
- RESOLVE Physician Advisory Group
- Washington State Obstetrical Association
- Society of Reproductive Surgeons
- Society for Assisted Reproductive Technologies
- American Medical Association
Honors
- Resident Teaching Award, USAF, 1980
- Memorial Foundation Award, Pacific Coast Obstetrics and Gynecology Society, 1981
- Distinguished Citizen Award, State of Washington, 1987
- President, Society of Reproductive Endocrinology and Infertility, 1994-95
- Best Doctors in America, 2nd edition, 1994-95
- Best Doctors in America: Pacific Region, 1996-97
- The 1000 Best Doctors in America, 1996-97
- Best Doctors for Women's Reproductive Endocrinologists, Good Housekeeping, August 1997
- Seattle's Top Physicians in Obstetrics and Gynecology, Seattle Magazine, March 1998
- President, American Society for Reproductive Medicine, 2000-2001
- Best Doctors in Seattle (Seattle Magazine, 2000)
- Best Doctors (bestdoctors.com, 2001)
- Best Doctors (Seattle Magazine, 2002)
- America's Top Doctors, 2002
Publications:
Soules MR, Steiner RA, Clifton DK, Cohen N, Aksel S, Bremner WJ. Progesterone modulation of pulsatile luteinizing hormone secretion in normal women. J Clin Endocrinol Metab 1984;58:378.
Soules MR, Steiner RA, Cohen NL, Bremner WJ, Clifton DK. Nocturnal slowing of pulsatile luteinizing hormone secretion in women during the follicular phase of the menstrual cycle. J Clin Endocrinol Metab 1985;61:43.
Soules MR, Clifton DK, Bremner WJ, Steiner RA. Corpus luteum insufficiency induced by a rapid gonadotropin-releasing hormone-induced gonadotropin secretion pattern in the follicular phase. J Clin Endocrinol Metab 1987;65:457.
Soules MR, Clifton DK, Cohen NL, Bremner WJ, Steiner RA. Luteal phase deficiency: abnormal gonadotropin and progesterone secretion patterns. J Clin Endocrinol Metab 1989;69:813.
Klein NA, Illingworth PJ, Groome NP, McNeilly AS, Battaglia DE, Soules MR. Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: A study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles. J Clin Endocrinol Metab 1996;81:2742
Klein NA, Battaglia DE, Fujimoto VF, Davis GS, Bremner WJ, Soules MR. Reproductive aging: accelerated ovarian follicular development associated with a monotropic FSH rise in normal older women. J Clin Endocrinol Metab 1996;81:1038.|
Klein NA, Battaglia DE, Miller PB, Branigan EF, Giudice LC, Soules MR. Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age. J Clin Endocrinol Metab 1996;81:1946.
Battaglia DE, Goodwin P, Klein NA, Soules MR. Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women. Human Reprod 1996;11:2217.
Klein NA, Battaglia DE, Woodruff TK, Padmanabhan V, Giudice LC, Groome NP, Bremner WJ, Soules MR. Ovarian follicular concentrations of follistatin, inhibin, IGF-I, IGF-II, IGFBP-2, IGFBP-3, and VEGF spontaneous menstrual cycles of normal women of advanced reproductive age. J Clin Endocrinol Metab 2000;85(12):4520.
Klein NA, Harper AJ Houmard BS, Soules MR. Is the short follicular phase in older women secondary to advanced or accelerated dominant follicle development? J Clin Endocrinol Metab, 2002.
Hansen KR, Knowlton NS, Thyer AC, Charleston JS, Soules MR, Klein NA. A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause.Human Reproduction, 2008; Vol.23, No.3 pp. 699-708.
