Michael R. Soules, MD

Managing Partner of Seattle Reproductive Medicine

Specialties-Reproductive Endocrinology & Infertility:

• Assisted reproductive technologies, including IVF
• Uterine anomalies
• Polycystic ovarian syndrome
• Ovarian Aging
• Endometriosis
• Menstrual cycle abnormalities
• Complex infertility problems with multiple problems
• Luteal phase deticipucy

Licensure:

• State of Washington, 1980

Board Certification:

• Obstetrics and Gynecology, 1979 (recertified 1993)
• Reproductive Endocrinology and Infertility, 1981 (recertified 1993, 1999, 2002)

Education:

• MD degree (University of California Los Angeles, 1972)
• Residency in Obstetrics and Gynecology (University of Colorado, 1976)
• Fellowship in Reproductive Endocrinology and Infertility (Duke University, 1978)
• Management Program (School of Business, University of Washington, 1990)

Research Interests:

• Reproductive aging
• Luteal phase deficiency
• Inhibin/activin

Current Research:

• Reproductive Aging in Normal Premenopausal Women
• New Protocol for IVF Ovulation Induction
• Acqueous Progesterone for use in ART

Affiliations:

• American College of Obstetricians and Gynecologists
• American Society for Reproductive Medicine
• Pacific Coast Reproductive Society
• Society of Reproductive Endocrinology and Infertility
• Society for Gynecologic Investigation
• American Gynecological and Obstetrical Society
• European Society of Human Reproduction and Embryology
• International Federation of Gynecology and Obstetrics
• King County Medical Society
• RESOLVE Physician Advisory Group
• Washington State Obstetrical Association
• Society of Reproductive Surgeons
• Society for Assisted Reproductive Technologies
• American Medical Association
  

Honors:

• Resident Teaching Award, USAF, 1980
• Memorial Foundation Award, Pacific Coast Obstetrics and Gynecology Society, 1981
• Distinguished Citizen Award, State of Washington, 1987
• President, Society of Reproductive Endocrinology and Infertility, 1994-95
• Best Doctors in America, 2nd edition, 1994-95
• Best Doctors in America: Pacific Region, 1996-97
• The 1000 Best Doctors in America, 1996-97
• Best Doctors for Women's Reproductive Endocrinologists, Good Housekeeping, August 1997
• Seattle's Top Physicians in Obstetrics and Gynecology, Seattle Magazine, March 1998
• President, American Society for Reproductive Medicine, 2000-2001
• Best Doctors in Seattle (Seattle Magazine, 2000)
• Best Doctors (bestdoctors.com, 2001)
• Best Doctors (Seattle Magazine, 2002)
• America's Top Doctors, 2002

Publications:

Soules MR, Steiner RA, Clifton DK, Cohen N, Aksel S, Bremner WJ. Progesterone modulation of pulsatile luteinizing hormone secretion in normal women. J Clin Endocrinol Metab 1984;58:378.

Soules MR, Steiner RA, Cohen NL, Bremner WJ, Clifton DK. Nocturnal slowing of pulsatile luteinizing hormone secretion in women during the follicular phase of the menstrual cycle. J Clin Endocrinol Metab 1985;61:43.

Soules MR, Clifton DK, Bremner WJ, Steiner RA. Corpus luteum insufficiency induced by a rapid gonadotropin-releasing hormone-induced gonadotropin secretion pattern in the follicular phase. J Clin Endocrinol Metab 1987;65:457.

Soules MR, Clifton DK, Cohen NL, Bremner WJ, Steiner RA. Luteal phase deficiency: abnormal gonadotropin and progesterone secretion patterns. J Clin Endocrinol Metab 1989;69:813.

Klein NA, Illingworth PJ, Groome NP, McNeilly AS, Battaglia DE, Soules MR. Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: A study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles. J Clin Endocrinol Metab 1996;81:2742

Klein NA, Battaglia DE, Fujimoto VF, Davis GS, Bremner WJ, Soules MR. Reproductive aging: accelerated ovarian follicular development associated with a monotropic FSH rise in normal older women. J Clin Endocrinol Metab 1996;81:1038.|

Klein NA, Battaglia DE, Miller PB, Branigan EF, Giudice LC, Soules MR. Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age. J Clin Endocrinol Metab 1996;81:1946.

Battaglia DE, Goodwin P, Klein NA, Soules MR. Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women. Human Reprod 1996;11:2217.

Klein NA, Battaglia DE, Woodruff TK, Padmanabhan V, Giudice LC, Groome NP, Bremner WJ, Soules MR. Ovarian follicular concentrations of follistatin, inhibin, IGF-I, IGF-II, IGFBP-2, IGFBP-3, and VEGF spontaneous menstrual cycles of normal women of advanced reproductive age. J Clin Endocrinol Metab 2000;85(12):4520.

Klein NA, Harper AJ Houmard BS, Soules MR. Is the short follicular phase in older women secondary to advanced or accelerated dominant follicle development? J Clin Endocrinol Metab, 2002.

Hansen KR, Knowlton NS, Thyer AC, Charleston JS, Soules MR, Klein NA. A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause.Human Reproduction, 2008; Vol.23, No.3 pp. 699–708.

Revised April 21, 2008